Levelsio Develops Alzheimer's Drug in Garage, SaaS Acquisition Market Highlights, and New Collaboration Tool

Key Takeaways

1. Levelsio invented a novel Alzheimer's drug (PAC-832), claiming it's the world's first selective GalR1 antagonist, synthesized in his home garage lab.
2. Levelsio detailed a live-editing workflow using Claude Code on VPS for production servers, signaling a shift toward cloud-based AI coding.
3. acquire.com listed several startups for sale, including an AI biohacking app ($12M TTM revenue, asking $12M) and a sleep health brand ($23.2M TTM, asking $7M).
4. Zach achieved $1M ARR in 19 months by selling SaaS to agencies instead of brands, leveraging platform partner directories.
5. Alex Lieberman launched Multi, a tool that turns any webpage into a collaborative space for comments and AI queries.

1. Breakthrough Alzheimer's Drug and AI Coding Workflow

1. Levelsio (@levelsio) announced the invention of PAC-832, a novel Alzheimer's drug described as the world's first selective GalR1 antagonist, designed and synthesized in his own garage chemistry lab. — via 1
2. Levelsio shared a coding workflow using Claude Code to live-edit production servers on a VPS, emphasizing that AI coding will increasingly move to cloud-based operations and the importance of backups. — via 1

2. SaaS Acquisition Market Activity and Buyer Insights

1. acquire.com (@acquiredotcom) listed multiple startups for sale, including an AI-driven biohacking app (TTM revenue $11.8M, asking $12M), a sleep health brand (TTM revenue $23.2M, asking $7M), a social media automation platform (TTM revenue $132.9K, asking $132K), and a Shopify sports nutrition dropshipping store (TTM revenue $52K, asking $52K). — via 1 2 3 4
2. Based on thousands of acquisitions, buyers fall into three categories: operators (run it themselves), portfolio buyers (profit & system efficiency), and strategic buyers (acquire to accelerate existing business, often paying highest multiples). Sellers who understand buyer types and adjust their pitch increase deal efficiency. — via 1
3. Flippa (@Flippa) listed a YouTube SaaS business for sale with $1.1M annual revenue, $597K profit, 7,400 active subscribers, and 88K monthly page views. — via 1

3. Entrepreneurial Tactics and New Tools

1. Zach achieved $1M ARR in 19 months by selling SaaS to agencies rather than brands, noting that agencies can be easily found through partner directories of platforms like Shopify and Klaviyo. — via 1
2. Alex Lieberman (@businessbarista) launched Multi, a tool that turns any webpage into a collaborative space where users can comment, reply, or ask AI questions, applicable for customer feedback, internal doc review, and team reading discussions. — via 1